Lovers in a Dangerous Time: Ecologically Motivated Relationship Safety Regulation

Pragmatic Regulation in Dangerous Times

Copper/MYC/CTR1 interplay: a dangerous relationship in hepatocellular carcinoma

Free serum copper correlates with tumor incidence and progression of human cancers, including hepatocellular carcinoma (HCC). Copper extracellular uptake is provided by the transporter CTR1, whose expression is regulated to avoid excessive intracellular copper entry. Inadequate copper serum concentration is involved in the pathogenesis of Non Alcoholic Fatty Liver Disease (NAFLD), which is beco...

HIV and T follicular helper cells: a dangerous relationship.

HIV infection leads to progressive destruction of infected CD4 T cells, hypergammaglobulinemia, and loss of memory B cells. Germinal centers, which are key to memory B cell formation and protective antibody responses, are major HIV reservoirs in which the virus replicates within T follicular helper (TFH) cells. In this issue of the JCI, the Koup and Streeck groups report that chronic SIV/HIV in...

Men, women & alcohol: a distinctly unequal & dangerous relationship.

This article illustrates how women who abuse alcohol are at greater risk physically, emotionally and socially than their male counterparts. As a result, I recommend that clinical assessment and underwriting of women, who abuse or have the potential to abuse alcohol, change to reflect the increased risks which these women face.

Exploring the Betrothed Lovers

We present the ongoing activities and the first results achieved in a research project concerning the understanding of narrative in the high school. Students and teachers experimented with new ways to learn linguistic and digital skills, by using a collaborative learning environment built around the novel I Promessi Sposi. We analyzed the literary text, extracting social networks of characters ...